CDK5RAP3

Across TCGA cell cohorts, CDK5RAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,230 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDK5RAP3-associated GO terms across cancer lineages are Chiasma assembly, Taurine biosynthetic process, and Alkanesulfonate biosynthetic process. Each is linked with CDK5RAP3 in more than 16 cancer types. Because this analysis shows association rather than direction, both CDK5RAP3-to-partner and partner-to-CDK5RAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chiasma assembly grouped by CDK5RAP3-low versus CDK5RAP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP3→partner) and Y-score (partner→CDK5RAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chiasma assembly →	+0.352	+0.849	.004	<.001	3	17
BONE	Taurine biosynthetic process →	+0.857	+0.585	<.001	.001	3	15
BONE	Alkanesulfonate biosynthetic process →	+0.857	+0.585	<.001	.001	3	15
URINARY_TRACT	Flagellated sperm motility →	-0.134	-0.875	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.118	-0.981	<.001	<.001	3	14
LARGE_INTESTINE	mRNA splice site recognition →	+0.144	+0.881	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,230 associations by consensus.

Chiasma assembly by CDK5RAP3 expression — BONE

Explore this box plot interactively →