CDK5RAP1

Across TCGA patient cohorts, CDK5RAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,097 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CDK5RAP1-associated genes across cancer lineages are FLT3, RAB27A, and LY86. Each is linked with CDK5RAP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDK5RAP1-to-partner and partner-to-CDK5RAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK5RAP1 versus FLT3 in BRCA, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP1→partner) and Y-score (partner→CDK5RAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FLT3 →	-0.957	-0.306	.001	.004	3	4
OV	RAB27A →	-0.769	-0.439	<.001	<.001	3	4
LUAD	LY86 →	-0.801	-0.500	<.001	<.001	3	4
LUAD	SAMD3 →	-0.441	-0.400	.001	.001	3	4
LUAD	IL16 →	-0.645	-0.519	<.001	<.001	3	4
BRCA	CERT1 →	-0.431	-0.236	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,097 associations by consensus.

CDK5RAP1 vs FLT3 — BRCA

Explore this scatter interactively →