CDK5RAP1

Across TCGA cell cohorts, CDK5RAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,671 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK5RAP1-associated GO terms across cancer lineages are Double-strand break repair, Interstrand cross-link repair, and Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11). Each is linked with CDK5RAP1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CDK5RAP1-to-partner and partner-to-CDK5RAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair grouped by CDK5RAP1-low versus CDK5RAP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5RAP1→partner) and Y-score (partner→CDK5RAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Double-strand break repair →	+0.054	+0.395	.005	.006	3	13
OESOPHAGUS	Interstrand cross-link repair →	+0.104	+0.780	<.001	.003	3	12
PANCREAS	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.110	+0.532	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of t-circle formation →	+0.144	+0.701	<.001	<.001	3	12
OESOPHAGUS	Microtubule organizing center organization →	+0.106	+0.656	.002	.005	2	13
OESOPHAGUS	Centrosome cycle →	+0.108	+0.681	.003	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,671 associations by consensus.

Double-strand break repair by CDK5RAP1 expression — BONE

Explore this box plot interactively →