CDK5R1

Across TCGA patient cohorts, CDK5R1 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,666 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK5R1-associated proteins across cancer lineages are CLINT1, IQGAP2, and PPP3CA_S462. Each is linked with CDK5R1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDK5R1-to-partner and partner-to-CDK5R1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK5R1 versus CLINT1 in COAD, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5R1→partner) and Y-score (partner→CDK5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CLINT1 →	-0.269	-0.502	<.001	<.001	3	6
BRCA	IQGAP2 →	-0.693	-0.727	<.001	<.001	3	6
BRCA	PPP3CA_S462 →	+1.122	+0.753	.004	.004	3	6
GBM	PARP4 →	-0.629	-1.527	<.001	<.001	3	5
LUAD	SGSM3 →	-0.421	-0.508	<.001	<.001	3	5
GBM	HSP90B1 →	-0.342	-1.157	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,666 associations by consensus.

CDK5R1 vs CLINT1 — COAD

Explore this scatter interactively →