CDK5R1

Across TCGA cell cohorts, CDK5R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,532 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CDK5R1-associated GO terms across cancer lineages are Microtubule organizing center organization, Microtubule polymerization or depolymerization, and P-body assembly. Each is linked with CDK5R1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CDK5R1-to-partner and partner-to-CDK5R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by CDK5R1-low versus CDK5R1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5R1→partner) and Y-score (partner→CDK5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Microtubule organizing center organization →	+0.089	+1.038	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.100	+0.866	<.001	<.001	3	12
PANCREAS	P-body assembly →	+0.069	+0.575	<.001	<.001	3	12
PANCREAS	Transcription initiation-coupled chromatin remodeling →	+0.090	+1.056	<.001	<.001	3	12
LUNG_SCLC	Regulation of DNA repair →	+0.073	+1.997	<.001	<.001	3	12
OVARY	DNA-templated transcription initiation →	+0.063	+0.691	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,532 associations by consensus.

Microtubule organizing center organization by CDK5R1 expression — PANCREAS

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