CDK5R1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CDK5R1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDK5R1-associated genes across cancer lineages are SLC10A2. Each is linked with CDK5R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK5R1-to-partner and partner-to-CDK5R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC10A2 grouped by CDK5R1-low versus CDK5R1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK5R1→partner) and Y-score (partner→CDK5R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINSLC10A2 →+0.006+6.022<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

SLC10A2 by CDK5R1 expression — SKIN

Box plot of SLC10A2 in CDK5R1-low vs CDK5R1-high samples in SKIN.

Explore this box plot interactively →

Exploration