CDK3

Across TCGA cell cohorts, CDK3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible CDK3-associated genes across cancer lineages are KRTAP13-2 and ARMH2. Each is linked with CDK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK3-to-partner and partner-to-CDK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP13-2 grouped by CDK3-low versus CDK3-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK3→partner) and Y-score (partner→CDK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	KRTAP13-2 →	+0.229	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	ARMH2 →	+0.020	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP13-2 by CDK3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →