CDK20

Across TCGA cell cohorts, CDK20 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDK20-associated genes across cancer lineages are OR4F4, LILRA1, and GOLGA6L1. Each is linked with CDK20 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK20-to-partner and partner-to-CDK20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4F4 grouped by CDK20-low versus CDK20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK20→partner) and Y-score (partner→CDK20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.019	+3.103	<.001	.004	3	2
OVARY	LILRA1 →	+0.011	+4.228	<.001	.006	3	1
OVARY	GOLGA6L1 →	+0.019	+4.029	.001	.009	3	1
LARGE_INTESTINE	C6orf118 →	+0.146	+3.115	<.001	.004	3	1
LARGE_INTESTINE	TBR1 →	+0.040	+3.333	<.001	.009	3	1
LARGE_INTESTINE	COX6A2 →	+0.058	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR4F4 by CDK20 expression — LARGE_INTESTINE

Explore this box plot interactively →