CDK19

Across TCGA patient cohorts, CDK19 protein abundance is significantly associated with the RNA expression of many other genes, with 7,865 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDK19-associated genes across cancer lineages are CCDC96, MMS22L, and LIN9. Each is linked with CDK19 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDK19-to-partner and partner-to-CDK19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK19 versus CCDC96 in UCEC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK19→partner) and Y-score (partner→CDK19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC96 →	-0.776	-0.200	<.001	<.001	3	4
HNSC	MMS22L →	+0.645	+0.325	<.001	<.001	3	4
BRCA	LIN9 →	+0.734	+0.352	<.001	<.001	3	4
LSCC	KATNA1 →	+0.511	+0.341	<.001	<.001	3	4
HNSC	LYRM2 →	+0.494	+0.287	.008	.002	3	4
BRCA	HDAC2 →	+0.807	+0.332	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,865 associations by consensus.

CDK19 vs CCDC96 — UCEC

Explore this scatter interactively →