CDK19

Across TCGA patient cohorts, CDK19 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,099 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDK19-associated proteins across cancer lineages are CDC40, ADNP, and SMARCE1. Each is linked with CDK19 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK19-to-partner and partner-to-CDK19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK19 versus CDC40 in GBM, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK19→partner) and Y-score (partner→CDK19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDC40 →	+0.327	+0.505	<.001	.001	2	7
LSCC	ADNP →	+0.425	+0.360	<.001	<.001	3	6
HNSC	SMARCE1 →	+0.343	+0.309	<.001	<.001	3	6
HNSC	MED23 →	+0.296	+0.417	<.001	<.001	3	6
HNSC	HDAC2 →	+0.367	+0.339	<.001	<.001	3	6
HNSC	ARID1B →	+0.334	+0.390	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,099 associations by consensus.

CDK19 vs CDC40 — GBM

Explore this scatter interactively →