CDK19

Across TCGA patient cohorts, CDK19 mutation is significantly associated with the RNA expression of many other genes, with 1,239 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK19-associated genes across cancer lineages are LINC01248, NFYCP2, and TOMM22P5. Each is linked with CDK19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK19-to-partner and partner-to-CDK19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01248 grouped by CDK19-low versus CDK19-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK19→partner) and Y-score (partner→CDK19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01248 →	+0.224	+3.779	<.001	.003	3	2
COAD	NFYCP2 →	+0.290	+3.070	<.001	.005	3	2
COAD	TOMM22P5 →	+0.453	+4.019	.001	.001	3	2
COAD	ACTR3P2 →	+0.507	+3.628	<.001	.003	3	2
COAD	KPNA2P1 →	+0.178	+3.716	<.001	.003	3	2
COAD	LSM6P2 →	+0.633	+3.233	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,239 associations by consensus.

LINC01248 by CDK19 expression — COAD

Explore this box plot interactively →