CDK18

Across TCGA patient cohorts, CDK18 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,493 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK18-associated proteins across cancer lineages are CDK18_S89, CDK18_S14, and CDK18_S98. Each is linked with CDK18 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDK18-to-partner and partner-to-CDK18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK18 versus CDK18_S89 in BRCA, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK18→partner) and Y-score (partner→CDK18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDK18_S89 →	+0.875	+1.313	<.001	<.001	3	9
GBM	CDK18_S14 →	+0.946	+1.225	<.001	<.001	3	8
LUAD	CDK18_S98 →	+0.778	+0.635	.001	.001	3	6
BRCA	CDK18_S132 →	+1.263	+0.971	<.001	<.001	3	6
GBM	CDK18_S117 →	+0.904	+1.111	<.001	<.001	3	5
COAD	SCCPDH_S217 →	+0.896	+1.041	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,493 associations by consensus.

CDK18 vs CDK18_S89 — BRCA

Explore this scatter interactively →