CDK18

Across TCGA patient cohorts, CDK18 protein abundance is significantly associated with the RNA expression of many other genes, with 11,271 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK18-associated genes across cancer lineages are LEMD1, CLCA4, and CXCR2. Each is linked with CDK18 in more than 4 cancer types. Because this analysis shows association rather than direction, both CDK18-to-partner and partner-to-CDK18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK18 versus LEMD1 in PDAC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK18→partner) and Y-score (partner→CDK18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LEMD1 →	+1.361	+0.315	<.001	.002	3	5
LSCC	CLCA4 →	+1.387	+0.356	.001	<.001	3	4
LSCC	CXCR2 →	+1.112	+0.442	<.001	<.001	3	4
LUAD	CLEC5A →	+0.577	+0.293	.008	<.001	3	4
LSCC	CSF3R →	+1.139	+0.496	<.001	<.001	3	4
LUAD	BLACAT1 →	+0.962	+0.367	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,271 associations by consensus.

CDK18 vs LEMD1 — PDAC

Explore this scatter interactively →