CDK17

Across TCGA cell cohorts, CDK17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,099 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK17-associated GO terms across cancer lineages are Centriole-centriole cohesion, Dephosphorylation, and Cold acclimation. Each is linked with CDK17 in more than 10 cancer types. Because this analysis shows association rather than direction, both CDK17-to-partner and partner-to-CDK17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Centriole-centriole cohesion grouped by CDK17-low versus CDK17-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK17→partner) and Y-score (partner→CDK17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Centriole-centriole cohesion →	+0.066	+0.854	<.001	<.001	3	11
CNS	Dephosphorylation →	+0.034	+0.642	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cold acclimation →	+0.146	+0.807	.001	.003	3	10
LARGE_INTESTINE	Centrosome duplication →	+0.097	+1.081	<.001	<.001	3	10
OESOPHAGUS	L-amino acid metabolic process →	-0.084	-0.896	<.001	<.001	3	10
BLOOD_Leukemia	Dentate gyrus development →	+0.097	+0.634	.004	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,099 associations by consensus.

Centriole-centriole cohesion by CDK17 expression — BLOOD_Leukemia

Explore this box plot interactively →