CDK17

Across TCGA cell cohorts, CDK17 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK17-associated genes across cancer lineages are OR10G2, AVP, and OR7D4. Each is linked with CDK17 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK17-to-partner and partner-to-CDK17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G2 grouped by CDK17-low versus CDK17-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK17→partner) and Y-score (partner→CDK17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10G2 →	+1.565	+4.551	<.001	.004	3	2
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	2
OVARY	OR7D4 →	+0.056	+5.196	<.001	.005	3	1
BLOOD_Lymphoma	C18orf63 →	+0.019	+4.867	<.001	.009	3	1
BLOOD_Leukemia	IFNG →	+0.233	+4.152	<.001	.009	3	1
BLOOD_Leukemia	SPATA19 →	+0.022	+5.569	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR10G2 by CDK17 expression — BLOOD_Leukemia

Explore this box plot interactively →