CDK16

Across TCGA patient cohorts, CDK16 protein abundance is significantly associated with the RNA expression of many other genes, with 11,722 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK16-associated genes across cancer lineages are USP27X, SLC4A3, and KCMF1. Each is linked with CDK16 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDK16-to-partner and partner-to-CDK16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK16 versus USP27X in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK16→partner) and Y-score (partner→CDK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	USP27X →	+0.435	+0.407	.005	.002	3	4
UCEC	SLC4A3 →	+0.965	+0.270	.001	.003	3	4
BRCA	KCMF1 →	+0.498	+0.374	<.001	<.001	3	4
BRCA	CALU →	+0.779	+0.337	<.001	<.001	3	4
OV	JADE3 →	+0.746	+0.418	<.001	<.001	3	3
OV	UBA1 →	+0.992	+0.516	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,722 associations by consensus.

CDK16 vs USP27X — OV

Explore this scatter interactively →