CDK16

Across TCGA cell cohorts, CDK16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,678 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDK16-associated GO terms across cancer lineages are Growth hormone secretion, Post-Golgi vesicle-mediated transport, and Regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with CDK16 in more than 18 cancer types. Because this analysis shows association rather than direction, both CDK16-to-partner and partner-to-CDK16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by CDK16-low versus CDK16-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK16→partner) and Y-score (partner→CDK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Growth hormone secretion →	+0.168	+1.212	<.001	<.001	3	19
BREAST	Post-Golgi vesicle-mediated transport →	+0.072	+1.031	.003	.001	3	14
LARGE_INTESTINE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.139	+0.958	<.001	<.001	3	13
LARGE_INTESTINE	Positive regulation of TORC2 signaling →	+0.088	+0.743	<.001	<.001	3	12
BLOOD_Myeloma	Regulation of heterochromatin formation →	+0.094	+0.890	.001	<.001	3	12
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.155	+1.047	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,678 associations by consensus.

Growth hormone secretion by CDK16 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →