CDK14

Across TCGA patient cohorts, CDK14 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,568 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK14-associated proteins across cancer lineages are PDLIM4, PDLIM7, and CAVIN3. Each is linked with CDK14 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDK14-to-partner and partner-to-CDK14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK14 versus PDLIM4 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK14→partner) and Y-score (partner→CDK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDLIM4 →	+0.542	+0.837	<.001	<.001	3	8
BRCA	PDLIM7 →	+0.672	+0.999	<.001	<.001	3	8
BRCA	CAVIN3 →	+0.765	+0.887	<.001	<.001	3	8
BRCA	CLPX →	-0.286	-0.998	<.001	<.001	3	8
COAD	FERMT2 →	+0.425	+0.692	<.001	<.001	3	8
LSCC	MMP2 →	+0.755	+0.836	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,568 associations by consensus.

CDK14 vs PDLIM4 — BRCA

Explore this scatter interactively →