CDK14

Across TCGA patient cohorts, CDK14 protein abundance is significantly associated with the RNA expression of many other genes, with 13,090 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK14-associated genes across cancer lineages are CDH11, SYNDIG1, and AEBP1. Each is linked with CDK14 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK14-to-partner and partner-to-CDK14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK14 versus CDH11 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK14→partner) and Y-score (partner→CDK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDH11 →	+1.316	+0.410	<.001	.001	3	7
BRCA	SYNDIG1 →	+1.380	+0.500	<.001	<.001	3	6
CCRCC	AEBP1 →	+2.034	+0.325	<.001	<.001	3	6
UCEC	BNC2 →	+1.467	+0.652	<.001	<.001	3	6
UCEC	TVP23CP1 →	+1.416	+0.715	<.001	<.001	3	6
UCEC	PTP4A1P3 →	+1.711	+0.788	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,090 associations by consensus.

CDK14 vs CDH11 — BRCA

Explore this scatter interactively →