CDK14

Across TCGA cell cohorts, CDK14 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CDK14-associated genes across cancer lineages are ARSF, MAGEB5, and OR5B21. Each is linked with CDK14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK14-to-partner and partner-to-CDK14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARSF grouped by CDK14-low versus CDK14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK14→partner) and Y-score (partner→CDK14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ARSF →	+0.327	+4.705	<.001	.003	3	2
OESOPHAGUS	MAGEB5 →	+0.040	+4.906	<.001	.006	3	1
OESOPHAGUS	OR5B21 →	+0.023	+4.906	<.001	.006	3	1
STOMACH	CD40LG →	+0.019	+4.432	<.001	.003	3	1
BLOOD_Leukemia	SOX3 →	+0.021	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR6M1 →	+0.016	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

ARSF by CDK14 expression — BLOOD_Leukemia

Explore this box plot interactively →