CDK13

Across TCGA cell cohorts, CDK13 mutation is significantly associated with the RNA expression of many other genes, with 1,055 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDK13-associated genes across cancer lineages are ZNF831, CCL18, and VCY. Each is linked with CDK13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK13-to-partner and partner-to-CDK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF831 grouped by CDK13-low versus CDK13-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK13→partner) and Y-score (partner→CDK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ZNF831 →	+0.016	+5.000	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	CCL18 →	+0.031	+3.510	<.001	.007	3	2
BREAST	VCY →	+0.901	+4.672	<.001	.002	3	2
LARGE_INTESTINE	TTC33 →	+0.634	+2.545	<.001	<.001	3	2
LARGE_INTESTINE	CRBN →	+0.376	+2.126	.001	.004	3	2
LARGE_INTESTINE	MYBBP1A →	+0.597	+2.523	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,055 associations by consensus.

ZNF831 by CDK13 expression — PANCREAS

Explore this box plot interactively →