CDK11A

Across TCGA patient cohorts, CDK11A protein abundance is significantly associated with the RNA expression of many other genes, with 4,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDK11A-associated genes across cancer lineages are SLC35E2A, PABPC1P4, and ZNF263. Each is linked with CDK11A in more than 3 cancer types. Because this analysis shows association rather than direction, both CDK11A-to-partner and partner-to-CDK11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK11A versus SLC35E2A in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK11A→partner) and Y-score (partner→CDK11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC35E2A →	+0.774	+0.520	<.001	<.001	3	4
UCEC	PABPC1P4 →	-1.056	-0.324	.008	.003	3	3
UCEC	ZNF263 →	+0.512	+0.218	.007	.009	3	3
UCEC	CNTRL →	+0.563	+0.413	.001	.001	3	2
UCEC	NT5C →	+1.063	+0.280	.008	.005	3	2
BRCA	YEATS4 →	+0.489	+0.388	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,046 associations by consensus.

CDK11A vs SLC35E2A — GBM

Explore this scatter interactively →