Across TCGA patient cohorts, CDK10 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,502 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK10-associated proteins across cancer lineages are DHX38, SAMSN1, and HSDL1. Each is linked with CDK10 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDK10-to-partner and partner-to-CDK10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK10→partner) and Y-score (partner→CDK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX38 →	+0.259	+0.429	<.001	<.001	3	7
GBM	SAMSN1 →	-0.529	-0.449	.002	.001	3	5
OV	HSDL1 →	+0.471	+0.723	<.001	<.001	3	5
LSCC	RELB →	-0.269	-0.319	.001	.004	3	4
CCRCC	CD44 →	-0.737	-0.526	<.001	<.001	3	4
PDAC	CTNNA1 →	+0.380	+0.344	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,502 associations by consensus.

Exploration

CDK10 survival (RNA) · tumor vs normal (RNA) · all CDK10 data types