Across TCGA patient cohorts, CDK10 protein abundance is significantly associated with the RNA expression of many other genes, with 5,618 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDK10-associated genes across cancer lineages are OTX1, ANTXR2, and GIMAP8. Each is linked with CDK10 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDK10-to-partner and partner-to-CDK10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK10→partner) and Y-score (partner→CDK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OTX1 →	+1.232	+0.445	.009	.008	3	4
UCEC	ANTXR2 →	-0.812	-0.388	.001	.007	3	3
UCEC	GIMAP8 →	-0.989	-0.334	.001	.003	3	3
HNSC	ASS1P1 →	-0.808	-0.346	.003	<.001	3	3
LSCC	IFFO1 →	-0.508	-0.313	<.001	<.001	3	2
UCEC	RASL12 →	-1.083	-0.513	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,618 associations by consensus.

Exploration

CDK10 survival (RNA) · tumor vs normal (RNA) · all CDK10 data types