CDK1

Across TCGA pan-cancer cohorts, CDK1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CDK1 data layer compared with 29 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CDK1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CDK1 expression acts as an unfavorable survival marker.

COAD, CCRCC, and HNSC are the cancer types where CDK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	0.893	1.000	.029	18	view →
CCRCC	OS	Median	All	0.508	0.979	.006	17	view →
HNSC	OS	Quartile	All	0.258	1.000	.017	16	view →
LUAD	DFS	Quartile	All	0.513	0.837	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CDK1–COAD (DFS)

Open the COAD breakdown →