CDHR2

Across TCGA patient cohorts, CDHR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,988 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDHR2-associated proteins across cancer lineages are CES2, ARHGEF2, and MYO15B_S1025. Each is linked with CDHR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDHR2-to-partner and partner-to-CDHR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDHR2 versus CES2 in PDAC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR2→partner) and Y-score (partner→CDHR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CES2 →	+0.694	+0.954	<.001	<.001	3	4
CCRCC	ARHGEF2 →	-0.254	-1.715	.001	.001	3	3
LUAD	MYO15B_S1025 →	+1.677	+1.669	<.001	<.001	3	3
PDAC	NEK3 →	+0.452	+1.235	.002	.003	3	3
CCRCC	JUNB →	-0.297	-1.645	.008	<.001	3	3
CCRCC	KIFAP3 →	+0.203	+1.510	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,988 associations by consensus.

CDHR2 vs CES2 — PDAC

Explore this scatter interactively →