CDHR2

Across TCGA cell cohorts, CDHR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,997 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDHR2-associated GO terms across cancer lineages are Regulation of protein localization to nucleus, Negative regulation of cell growth involved in contact inhibition, and Cilium-dependent cell motility. Each is linked with CDHR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDHR2-to-partner and partner-to-CDHR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to nucleus grouped by CDHR2-low versus CDHR2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR2→partner) and Y-score (partner→CDHR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein localization to nucleus →	+0.081	+0.448	<.001	<.001	3	9
BLOOD_Lymphoma	Negative regulation of cell growth involved in contact inhibition →	-0.298	-0.230	.008	.002	3	9
SOFT_TISSUE	Cilium-dependent cell motility →	-0.074	-0.303	<.001	.001	3	9
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.109	+0.524	<.001	<.001	3	9
BONE	Negative regulation of DNA-templated transcription initiation →	+0.109	+0.524	<.001	<.001	3	9
SOFT_TISSUE	Cilium or flagellum-dependent cell motility →	-0.074	-0.303	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,997 associations by consensus.

Regulation of protein localization to nucleus by CDHR2 expression — SOFT_TISSUE

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