CDHR2

Across TCGA cell cohorts, CDHR2 mutation is significantly associated with the RNA expression of many other genes, with 1,755 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDHR2-associated genes across cancer lineages are ZMYND8, AK7, and OR4F21. Each is linked with CDHR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDHR2-to-partner and partner-to-CDHR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZMYND8 grouped by CDHR2-low versus CDHR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDHR2→partner) and Y-score (partner→CDHR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZMYND8 →	-0.638	-2.000	.004	.009	3	2
LARGE_INTESTINE	AK7 →	+0.764	+3.169	.001	.005	3	2
LARGE_INTESTINE	OR4F21 →	+0.079	+1.726	.002	.007	3	2
OESOPHAGUS	MARCHF11 →	+0.205	+3.836	.002	.004	3	1
OESOPHAGUS	SLITRK2 →	+0.062	+3.836	.003	.004	3	1
OESOPHAGUS	REM1 →	+0.024	+3.392	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,755 associations by consensus.

ZMYND8 by CDHR2 expression — LARGE_INTESTINE

Explore this box plot interactively →