CDH7

Across TCGA pan-cancer cohorts, CDH7 Mutation is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CDH7 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CDH7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CDH7 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, UCEC, and LUSC are the cancer types where CDH7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.380	0.878	<.001	33	view →
UCEC	OS	Median	All	0.938	0.644	.010	20	view →
LUSC	OS	Median	IV	0.001	0.673	.014	18	view →
BLCA	DFS	Median	III,IV	0.181	0.550	.016	18	view →
LUAD	OS	Median	III,IV	0.004	0.662	<.001	13	view →
CESC	OS	Median	All	0.149	0.591	.020	4	view →
BRCA	OS	Median	All	0.267	0.580	.040	2	view →
SKCM	OS	Median	All	0.148	0.407	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CDH7–COAD (OS)

Open the COAD breakdown →