CDH7

Across TCGA cell cohorts, CDH7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,109 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDH7-associated GO terms across cancer lineages are Morphogenesis of a branching structure, Positive regulation of dopamine receptor signaling pathway, and Folic acid transport. Each is linked with CDH7 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDH7-to-partner and partner-to-CDH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Morphogenesis of a branching structure grouped by CDH7-low versus CDH7-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH7→partner) and Y-score (partner→CDH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Morphogenesis of a branching structure →	-0.070	-0.428	<.001	.006	3	7
SKIN	Positive regulation of dopamine receptor signaling pathway →	-0.247	-0.645	<.001	<.001	3	6
BONE	Folic acid transport →	+0.136	+1.461	.003	.001	3	6
SKIN	Positive regulation of cell chemotaxis to fibroblast growth factor →	-0.721	-0.810	.003	.001	3	5
SKIN	Positive regulation of endothelial cell chemotaxis to fibroblast growth factor →	-0.721	-0.810	.003	.001	3	5
SKIN	Positive regulation of chemotaxis →	-0.097	-0.677	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,109 associations by consensus.

Morphogenesis of a branching structure by CDH7 expression — BREAST

Explore this box plot interactively →