CDH7

Across TCGA cell cohorts, CDH7 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH7-associated genes across cancer lineages are LCE1F, TRIML1, and KCNK18. Each is linked with CDH7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH7-to-partner and partner-to-CDH7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by CDH7-low versus CDH7-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH7→partner) and Y-score (partner→CDH7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LCE1F →	+0.330	+4.906	<.001	.006	3	2
LUNG_SCLC	TRIML1 →	+0.114	+2.684	<.001	.001	3	2
OESOPHAGUS	KCNK18 →	+0.020	+4.906	<.001	.006	3	1
PANCREAS	OPRPN →	+0.029	+5.000	<.001	.006	3	1
PANCREAS	REG1B →	+0.025	+5.000	<.001	.006	3	1
BLOOD_Lymphoma	NEUROD4 →	+0.090	+3.544	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

LCE1F by CDH7 expression — OESOPHAGUS

Explore this box plot interactively →