CDH6

Across TCGA patient cohorts, CDH6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,779 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDH6-associated proteins across cancer lineages are CDH6_S786, NID1, and TBX2_S360. Each is linked with CDH6 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDH6-to-partner and partner-to-CDH6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH6 versus CDH6_S786 in LSCC, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH6→partner) and Y-score (partner→CDH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDH6_S786 →	+1.335	+1.168	<.001	<.001	3	8
LSCC	NID1 →	+0.423	+1.134	<.001	<.001	3	5
PDAC	TBX2_S360 →	+0.699	+0.940	<.001	<.001	3	5
PDAC	FBLN5 →	+0.704	+0.907	<.001	<.001	3	5
BRCA	FERMT2 →	+0.590	+0.493	<.001	<.001	3	5
BRCA	PRG4 →	+0.400	+0.429	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,779 associations by consensus.

CDH6 vs CDH6_S786 — LSCC

Explore this scatter interactively →