CDH6

Across TCGA patient cohorts, CDH6 protein abundance is significantly associated with the RNA expression of many other genes, with 13,536 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CDH6-associated genes across cancer lineages are TSPAN1, GOLGA1, and RMI1. Each is linked with CDH6 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDH6-to-partner and partner-to-CDH6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH6 versus TSPAN1 in OV, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH6→partner) and Y-score (partner→CDH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TSPAN1 →	+1.709	+1.025	<.001	<.001	3	4
UCEC	GOLGA1 →	-0.526	-0.862	<.001	.003	3	3
LSCC	RMI1 →	-0.928	-0.824	<.001	<.001	3	3
HNSC	SLC8A1 →	+0.868	+1.081	.001	.001	3	3
GBM	BCHE →	+1.354	+0.554	<.001	<.001	3	3
LUAD	TKT →	-0.622	-0.273	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,536 associations by consensus.

CDH6 vs TSPAN1 — OV

Explore this scatter interactively →