CDH5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDH5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,998 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDH5-associated genes across cancer lineages are DIPK2B, BCL6B, and CD34. Each is linked with CDH5 in more than 8 cancer types. Because this analysis shows association rather than direction, both CDH5-to-partner and partner-to-CDH5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH5 versus DIPK2B in CCRCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH5→partner) and Y-score (partner→CDH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCDIPK2B →+1.223+0.675<.001<.00139
CCRCCBCL6B →+1.142+0.609<.001<.00139
CCRCCCD34 →+1.033+0.592<.001<.00139
CCRCCCLEC14A →+1.412+0.616<.001<.00139
CCRCCFLT4 →+1.201+0.625<.001<.00139
BRCACD93 →+0.868+0.490<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,998 associations by consensus.

CDH5 vs DIPK2B — CCRCC

Per-sample scatter of CDH5 vs DIPK2B in CCRCC (Pearson r = 0.78).

Explore this scatter interactively →

Exploration