CDH24

Across TCGA patient cohorts, CDH24 mutation is significantly associated with the RNA expression of many other genes, with 752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDH24-associated genes across cancer lineages are RNU6-340P, MIR548T, and LINC02559. Each is linked with CDH24 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH24-to-partner and partner-to-CDH24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-340P grouped by CDH24-low versus CDH24-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH24→partner) and Y-score (partner→CDH24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-340P →	+0.209	+4.584	<.001	.005	3	3
HNSC	MIR548T →	+0.383	+4.655	<.001	.007	3	2
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	2
HNSC	MMEL1-AS1 →	+1.273	+5.339	<.001	.003	3	2
LUAD	POTEF-AS1 →	+0.066	+4.739	<.001	.004	3	2
LUAD	FRG2B →	+0.146	+3.978	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 752 associations by consensus.

RNU6-340P by CDH24 expression — LUAD

Explore this box plot interactively →