CDH24

Across TCGA cell cohorts, CDH24 mutation is significantly associated with the RNA expression of many other genes, with 1,411 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH24-associated genes across cancer lineages are CALCOCO2, RETREG1, and GCAT. Each is linked with CDH24 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH24-to-partner and partner-to-CDH24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CALCOCO2 grouped by CDH24-low versus CDH24-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH24→partner) and Y-score (partner→CDH24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CALCOCO2 →	+0.799	+3.169	<.001	.006	3	3
LARGE_INTESTINE	RETREG1 →	+1.000	+2.265	.005	.001	3	3
LARGE_INTESTINE	GCAT →	+1.295	+2.949	<.001	<.001	3	2
LARGE_INTESTINE	CCDC134 →	+0.812	+4.043	<.001	<.001	3	2
LARGE_INTESTINE	CENPM →	+0.716	+2.265	<.001	.001	3	2
LARGE_INTESTINE	CBY1 →	+0.673	+3.482	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,411 associations by consensus.

CALCOCO2 by CDH24 expression — LARGE_INTESTINE

Explore this box plot interactively →