CDH18

Across TCGA pan-cancer cohorts, CDH18 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CDH18 data layer compared with 7 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CDH18 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CDH18 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

KIRC, UCS, and UVM are the cancer types where CDH18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.550	0.703	<.001	125	view →
UCS	OS	Tertile	II,III,IV	0.790	0.271	<.001	80	view →
UVM	DFS	Median	All	0.427	0.725	.001	68	view →
LIHC	DFS	Tertile	All	0.427	0.597	<.001	67	view →
SCLC	DFS	Tertile	All	0.269	0.550	<.001	65	view →
LUAD	DFS	Median	All	0.744	0.826	.002	59	view →
UCEC	DFS	Median	All	0.568	0.720	<.001	58	view →
LGG	DFS	Median	All	0.834	0.635	<.001	54	view →
KIRP	OS	Quartile	All	0.514	0.788	<.001	51	view →
THYM	OS	Median	All	0.841	1.000	.002	32	view →
BLCA	DFS	Quartile	All	0.519	0.658	.003	28	view →
ACC	DFS	Median	All	0.545	0.894	.003	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CDH18–KIRC (OS)

Open the KIRC breakdown →