CDH18-AS1

Across TCGA pan-cancer cohorts, CDH18-AS1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated CDH18-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CDH18-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CDH18-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

KIRP, BLCA, and SKCM are the cancer types where CDH18-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	54	view →
BLCA	OS	Tertile	IV	0.244	0.606	.008	36	view →
SKCM	OS	Tertile	III,IV	0.331	0.708	.004	36	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
LGG	OS	Tertile	All	0.364	0.812	.006	36	view →
ACC	OS	Tertile	All	0.147	0.685	.018	36	view →
LIHC	DFS	Tertile	II,III,IV	0.099	0.423	.003	24	view →
LAML	DFS	Tertile	All	0.869	0.320	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CDH18-AS1–KIRP (OS)

Open the KIRP breakdown →