CDH13

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CDH13 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CDH13 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CDH13 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CDH13 expression acts as an unfavorable survival marker, although some lineages such as GBM and CCRCC show a favorable association.

GBM, CCRCC, and LUAD are the cancer types where CDH13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSQuartileAll0.8380.565.00517view →
CCRCCDFSTertileIII,IV0.7320.375.00611view →
LUADDFSMedianAll0.8880.944.0194view →
LSCCOSMedianII,III,IV0.8101.000.0352view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CDH13–GBM (DFS)

Kaplan–Meier survival curve for CDH13 mass-spec protein-high vs -low samples in GBM.

Open the GBM breakdown →

Exploration