CDH13

Across TCGA cell cohorts, CDH13 mutation is significantly associated with the RNA expression of many other genes, with 237 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH13-associated genes across cancer lineages are ELAC1, TFAP2D, and IL1F10. Each is linked with CDH13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH13-to-partner and partner-to-CDH13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELAC1 grouped by CDH13-low versus CDH13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH13→partner) and Y-score (partner→CDH13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELAC1 →	+0.684	+3.385	.003	.004	3	2
UPPER_AERODIGESTIVE_TRACT	TFAP2D →	+0.077	+4.736	<.001	.009	3	2
BLOOD_Myeloma	IL1F10 →	+0.036	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TLE7 →	+0.006	+4.807	<.001	.006	3	1
LARGE_INTESTINE	DEPDC5 →	+0.605	+3.212	.003	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.601	+3.160	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

ELAC1 by CDH13 expression — LARGE_INTESTINE

Explore this box plot interactively →