CDH12P4

Across TCGA patient cohorts, CDH12P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,700 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDH12P4-associated GO terms across cancer lineages are Regulation of Ras protein signal transduction, Embryonic hindlimb morphogenesis, and Positive regulation of protein import into nucleus. Each is linked with CDH12P4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDH12P4-to-partner and partner-to-CDH12P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Ras protein signal transduction grouped by CDH12P4-low versus CDH12P4-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH12P4→partner) and Y-score (partner→CDH12P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Regulation of Ras protein signal transduction →	+0.018	+0.069	<.001	.001	3	3
UVM	Embryonic hindlimb morphogenesis →	+0.032	+0.091	.006	.008	2	3
ACC	Positive regulation of protein import into nucleus →	+0.037	+0.110	<.001	.004	3	2
KIRC	Positive regulation of cell-substrate adhesion →	+0.018	+0.044	.003	.001	3	2
KIRC	Regulation of actin filament organization →	+0.016	+0.045	.003	.001	3	2
KIRC	Integrated stress response signaling →	+0.020	+0.043	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,700 associations by consensus.

Regulation of Ras protein signal transduction by CDH12P4 expression — KIRC

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