CDH12

Across TCGA patient cohorts, CDH12 protein abundance is significantly associated with the RNA expression of many other genes, with 155 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDH12-associated genes across cancer lineages are SUSD6, FBXO31, and SLC1A5. Each is linked with CDH12 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH12-to-partner and partner-to-CDH12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH12 versus SUSD6 in GBM, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH12→partner) and Y-score (partner→CDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUSD6 →	-1.059	-1.096	.001	<.001	3	1
GBM	FBXO31 →	-0.604	-0.794	.002	.002	3	1
GBM	SLC1A5 →	-1.532	-0.948	.005	.004	3	1
GBM	GAB1 →	+0.864	+0.880	.001	.008	3	1
GBM	PRKAB1 →	-0.324	-0.827	<.001	<.001	3	1
GBM	ADGRG6 →	-1.646	-1.211	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 155 associations by consensus.

CDH12 vs SUSD6 — GBM

Explore this scatter interactively →