CDH12

Across TCGA cell cohorts, CDH12 RNA expression is significantly associated with the go_rna of many other GO terms, with 890 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDH12-associated GO terms across cancer lineages are Vesicle cargo loading, Lactate transport, and Lactate transmembrane transport. Each is linked with CDH12 in more than 6 cancer types. Because this analysis shows association rather than direction, both CDH12-to-partner and partner-to-CDH12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by CDH12-low versus CDH12-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH12→partner) and Y-score (partner→CDH12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Vesicle cargo loading →	+0.049	+0.286	.006	.009	3	7
STOMACH	Lactate transport →	-0.357	-1.900	<.001	.006	3	6
STOMACH	Lactate transmembrane transport →	-0.357	-1.900	<.001	.006	3	6
SKIN	Spliceosomal complex assembly →	+0.095	+1.302	<.001	.001	3	5
URINARY_TRACT	Cerebral cortex tangential migration →	+0.876	+1.011	.004	.004	3	5
OESOPHAGUS	Transcription elongation by RNA polymerase II →	+0.137	+1.348	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 890 associations by consensus.

Vesicle cargo loading by CDH12 expression — LARGE_INTESTINE

Explore this box plot interactively →