CDH11

Across TCGA cell cohorts, CDH11 mutation is significantly associated with the RNA expression of many other genes, with 537 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH11-associated genes across cancer lineages are ETDC, SLC28A1, and PRND. Each is linked with CDH11 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH11-to-partner and partner-to-CDH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETDC grouped by CDH11-low versus CDH11-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH11→partner) and Y-score (partner→CDH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	ETDC →	+0.593	+4.643	<.001	.008	3	2
SKIN	SLC28A1 →	+0.047	+3.878	.004	.003	3	2
BLOOD_Leukemia	PRND →	+0.007	+3.289	<.001	.009	3	2
URINARY_TRACT	DTHD1 →	+0.042	+4.087	<.001	.009	3	1
URINARY_TRACT	FABP9 →	+0.042	+4.087	<.001	.009	3	1
URINARY_TRACT	HBM →	+0.042	+4.087	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 537 associations by consensus.

ETDC by CDH11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →