CDH10

Across TCGA cell cohorts, CDH10 mutation is significantly associated with the RNA expression of many other genes, with 883 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CDH10-associated genes across cancer lineages are TGS1, CCDC117, and FOXR1. Each is linked with CDH10 in more than 3 cancer types. Because this analysis shows association rather than direction, both CDH10-to-partner and partner-to-CDH10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGS1 grouped by CDH10-low versus CDH10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH10→partner) and Y-score (partner→CDH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TGS1 →	+0.474	+1.628	.002	.007	3	3
LARGE_INTESTINE	CCDC117 →	+0.615	+3.541	<.001	<.001	3	3
SOFT_TISSUE	FOXR1 →	+0.084	+4.222	.003	.007	3	2
LUNG_NSCLC_LUSC	MAGED4 →	+1.567	+3.106	<.001	.004	3	2
BLOOD_Lymphoma	FAM177B →	+0.877	+3.392	.001	.004	3	2
BLOOD_Lymphoma	SCN4A →	+1.216	+3.201	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 883 associations by consensus.

TGS1 by CDH10 expression — LARGE_INTESTINE

Explore this box plot interactively →