CDH1

Across TCGA patient cohorts, CDH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDH1-associated proteins across cancer lineages are ESRP2, CTNNA1, and ERBB3_S686. Each is linked with CDH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDH1-to-partner and partner-to-CDH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH1 versus ESRP2 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH1→partner) and Y-score (partner→CDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ESRP2 →	+0.624	+0.804	<.001	<.001	3	8
HNSC	CTNNA1 →	+0.378	+0.810	<.001	<.001	3	7
GBM	ERBB3_S686 →	+0.729	+0.803	<.001	.001	3	6
BRCA	ESRP2_S573 →	+0.555	+1.068	.001	.006	3	6
LUAD	AP1M2 →	+0.379	+0.587	<.001	<.001	3	6
GBM	NNMT →	-1.209	-0.899	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,703 associations by consensus.

CDH1 vs ESRP2 — HNSC

Explore this scatter interactively →