CDH1

Across TCGA patient cohorts, CDH1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,287 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CDH1-associated genes across cancer lineages are GNG2, RAB33A, and ADAM19. Each is linked with CDH1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CDH1-to-partner and partner-to-CDH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH1 versus GNG2 in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH1→partner) and Y-score (partner→CDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GNG2 →	-0.802	-0.393	<.001	.004	3	8
OV	RAB33A →	-0.733	-0.556	<.001	<.001	3	7
UCEC	ADAM19 →	-1.050	-0.396	<.001	.002	2	8
COAD	PDE4B →	-0.862	-0.382	<.001	.001	3	7
HNSC	FTLP14 →	+1.027	+0.607	<.001	<.001	3	7
OV	IFFO1 →	-0.755	-0.646	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,287 associations by consensus.

CDH1 vs GNG2 — UCEC

Explore this scatter interactively →