CDH1

Across TCGA cell cohorts, CDH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,385 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CDH1-associated GO terms across cancer lineages are Regulation of inner ear receptor cell differentiation, Regulation of mechanoreceptor differentiation, and Establishment of epithelial cell apical/basal polarity. Each is linked with CDH1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CDH1-to-partner and partner-to-CDH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of inner ear receptor cell differentiation grouped by CDH1-low versus CDH1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH1→partner) and Y-score (partner→CDH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of inner ear receptor cell differentiation →	+1.265	+5.165	.003	<.001	3	12
URINARY_TRACT	Regulation of mechanoreceptor differentiation →	+1.265	+5.165	.003	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.214	-3.930	<.001	<.001	3	12
STOMACH	Response to indole-3-methanol →	+0.222	+4.132	<.001	<.001	3	12
STOMACH	Desmosome organization →	+0.439	+3.561	<.001	<.001	3	11
STOMACH	Maintenance of blood-brain barrier →	+0.220	+3.787	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,385 associations by consensus.

Regulation of inner ear receptor cell differentiation by CDH1 expression — URINARY_TRACT

Explore this box plot interactively →