CDCP1

Across TCGA patient cohorts, CDCP1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCP1-associated genes across cancer lineages are ATM, PDCD4, and Bcl-2. Each is linked with CDCP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CDCP1-to-partner and partner-to-CDCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by CDCP1-low versus CDCP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCP1→partner) and Y-score (partner→CDCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.449	-3.446	.005	.005	3	3
UCEC	PDCD4 →	-0.466	-1.990	.005	.030	3	2
UCEC	Bcl-2 →	-0.271	-2.439	.030	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+0.670	+2.019	.001	.005	3	2
SKCM	ERCC1 →	+0.126	+1.943	.031	.002	3	1
SKCM	MIG-6 →	+0.257	+1.297	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

ATM by CDCP1 expression — UCEC

Explore this box plot interactively →