CDCA7L

Across TCGA patient cohorts, CDCA7L mutation is significantly associated with the RNA expression of many other genes, with 3,345 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA7L-associated genes across cancer lineages are PHF5A, GPI, and TIMM22. Each is linked with CDCA7L in more than 2 cancer types. Because this analysis shows association rather than direction, both CDCA7L-to-partner and partner-to-CDCA7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHF5A grouped by CDCA7L-low versus CDCA7L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA7L→partner) and Y-score (partner→CDCA7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PHF5A →	+0.457	+1.893	<.001	<.001	3	3
UCEC	GPI →	+0.428	+2.094	.001	<.001	3	3
COAD	TIMM22 →	+0.709	+3.199	<.001	.009	3	3
UCEC	CHAF1A →	+0.710	+2.506	<.001	<.001	3	3
UCEC	PGAM1 →	+0.741	+2.758	<.001	<.001	3	3
UCEC	MRM3 →	+0.476	+1.935	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,345 associations by consensus.

PHF5A by CDCA7L expression — UCEC

Explore this box plot interactively →